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Welcome to the Cox Group

Selected Publications

J. Davison, A. al Fahad, M. Cai, Z. Song, S. Yehia, C. M. Lazarus, A. M. Bailey, T. J. Simpson and R. J. Cox,* Genetic, Molecular and Biochemical Basis of Fungal Tropolone Biosynthesis, Proc. Natl. Acad Sci USA, 2012, 109(20), 7642-7647.

K. M. Fisch, W. Bakeer, A. A. Yakasai, Z. Song, J. Pedrick, Z. Wasil, A. M. Bailey, C. M. Lazarus, T. J. Simpson and R. J. Cox,* Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Poliketide Synthases and Resurrect an Extinct Metabolite, J. Am. Chem. Soc., 2011, 133, 16635-16641.

A. A. Yakasai, J. Davison, Z. Wasil, L. Halo, C. P. Butts, C. M. Lazarus, A. M. Bailey, T. J. Simpson and R. J. Cox,* Nongenetic Reprogramming of a Fungal Highly Reducing Polyketide Synthase, J. Am. Chem. Soc., 2011, 133, 10990-10998.

M. N. Heneghan, A. A. Yakasai, L. M. Halo, Z. Song, A. M. Bailey, R. J. Cox,* T. J. Simpson and C. M. Lazarus, The First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multi-Gene Cluster, ChemBioChem, 2010, 11, 1508-1512.

P. Beltran-Alvarez, R. J. Cox,* J. Crosby and T. J. Simpson, Dissecting the Component Reactions Catalysed by the Actinorhodin Minimal Polyketide Synthase, Biochemistry, 2007, 46, 14672-14681.

R. J. Cox* and U. Wong, The Chemical Mechanism of D-1-deoxyxylulose-5-phoyphate reductoisomerase from Escherichia coli, Angew. Chem. Int. Ed. Engl., 2007, 46, 4926-4929.