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Welcome to the Cox Group

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Selected Publications

J. Davison, A. al Fahad, M. Cai, Z. Song, S. Yehia, C. M. Lazarus, A. M. Bailey, T. J. Simpson and R. J. Cox,* Genetic, Molecular and Biochemical Basis of Fungal Tropolone Biosynthesis, Proc. Natl. Acad Sci USA, 2012, 109(20), 7642-7647.

K. M. Fisch, W. Bakeer, A. A. Yakasai, Z. Song, J. Pedrick, Z. Wasil, A. M. Bailey, C. M. Lazarus, T. J. Simpson and R. J. Cox,* Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Poliketide Synthases and Resurrect an Extinct Metabolite, J. Am. Chem. Soc., 2011, 133, 16635-16641.

A. A. Yakasai, J. Davison, Z. Wasil, L. Halo, C. P. Butts, C. M. Lazarus, A. M. Bailey, T. J. Simpson and R. J. Cox,* Nongenetic Reprogramming of a Fungal Highly Reducing Polyketide Synthase, J. Am. Chem. Soc., 2011, 133, 10990-10998.

M. N. Heneghan, A. A. Yakasai, L. M. Halo, Z. Song, A. M. Bailey, R. J. Cox,* T. J. Simpson and C. M. Lazarus, The First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multi-Gene Cluster, ChemBioChem, 2010, 11, 1508-1512.

P. Beltran-Alvarez, R. J. Cox,* J. Crosby and T. J. Simpson, Dissecting the Component Reactions Catalysed by the Actinorhodin Minimal Polyketide Synthase, Biochemistry, 2007, 46, 14672-14681.

R. J. Cox* and U. Wong, The Chemical Mechanism of D-1-deoxyxylulose-5-phoyphate reductoisomerase from Escherichia coli, Angew. Chem. Int. Ed. Engl., 2007, 46, 4926-4929.